The effectiveness of continuous venovenous hemodiafiltration in phenobarbital intoxication

Carbamazepine Intoxication Unresponsive to Continuous Venovenous Hemodiafiltration

s: Carbamazepine (CBZ) intoxication can be associated with severe toxicity. Highly protein-bounded, CBZ is not removed efficiently through conventional hemodialysis. we observed that serum CBZ level was decreased minimally by albumin-enhanced CVVHDF with low dialysate flow. Therefore, albumin-enhanced CVVHDF with high dialysate flow should be considered in severe CBZ intoxication, if hemoperfus...

Pharmacokinetics of isepamicin during continuous venovenous hemodiafiltration.

The objective of this study was to analyze the pharmacokinetics of isepamicin during continuous venovenous hemodiafiltration. Six patients received 15 mg of isepamicin per kg of body weight. The mean isepamicin concentration peak in serum was 62.88 +/- 18.20 mg/liter 0.5 h after the infusion. The elimination half-life was 7. 91 +/- 0.83 h. The mean total body clearance was 1.75 +/- 0.28 liters/...

Successful resuscitation of a patient with continuous venovenous hemodiafiltration following intoxication from verapamil and trandolapril.

The incidence of accidental or intentional intoxication resulting from calcium channel blockers (CCBs) overdose has increased in recent years. We herein present the case of a female patient whose condition deteriorated even after she had received the maximum possible medical treatments following intoxication, but was successfully resuscitated following continuous hemodiafiltration (CHDF). A 26-...

Influence of continuous venovenous hemofiltration and continuous venovenous hemodiafiltration on the disposition of doripenem.

The pharmacokinetics, safety, and tolerability of a single 1-hour, 500-mg intravenous infusion of doripenem were assessed in dialysis-dependent subjects with stage 5 chronic kidney disease undergoing continuous renal replacement therapy (CRRT) via 12-hour continuous venovenous hemofiltration (CVVH) (n = 6) or continuous venovenous hemodiafiltration (CVVHDF) (n = 5). Healthy volunteers were also...

Continuous venovenous hemodiafiltration for renal failure and sepsis.